Eko Boys High School Lagos was founded 13 January 1913 by Rev. William Benjamin Euba. He was the former principal of Methodist Boys High School, Lagos, for seventeen years before establishing Eko Boys High School.

It was with a desire to establish an African Institution that would provide educational opportunities for the less privilege citizens of Lagos that Rev. Euba established this school. The school started with 28 students at 30 Broad street Lagos. Famous students from the school include Mr Bisi Onasanya – Group MD First Bank Nigeria, Chief Gabriel Igbinedion – Business man, Philanthropist, Former Oba of Lagos – Late Oba Oyekan.